THE RECOVERY TIME-COURSE OF CYP3A AFTER INDUCTION BY ST JOHN’S WORT ADMINISTRATION.
Thursday, July 24th, 2008This is engaging – a week to get from SJW initiation of 3A4 to lapse to solid state pre-induction levels of a 3A4 substrate. It suggests that week-on / week-off pulsing is a great gamble for “tricking” the hepatic churned oxidase complement in to progressing solid levels of a ... read more